Question 62676

Agenecalled“PRNP”producestheprionprotein.Inhumanstherearetwoallelesforthegene,
knownas“Met”and“Val”.PeoplewhoarehomozygousfortheMetallelecancontract
“variantCJD”,thefatalhumanformofmadcowdiseaseassociatedwiththeconsumptionof
infectedbeef.
InDenmark,asurveyof 352individualsfoundthat131werehomozygousforMet,168were
heterozygous,and53werehomozygousforVal.Is thePRNPgeneinHardy-Weinberg
equilibrium?Showyourcalculations.

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